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15.7. Childhood obesity intervention studies: A narrative review and guide for investigators, authors, editors, reviewers, journalists, and readers to guard against exaggerated effectiveness claims

AW Brown , DG Altman , T Baranowski , JM Bland , JA Dawson , NV Dhurandhar , S Dowla , KR Fontaine , A Gelman , SB Heymsfield , W Jayawardene , SW Keith , TK Kyle , E Loken , JM Oakes , J Stevens , DM Thomas , DB Allison

To read the full abstract: Obes Rev. 2019 Nov;20(11):15231541. doi: 10.1111/obr.12923.This is a thoughtful position statement by a number of leading obesity researchers and statisticians. They draw attention to 10 errors that are common in the scientific literature: 1. Using self-reported outcomes and teaching to the test (achieving better scores simply by repeat testing); 2. L...

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ey0016.4-11 | New Mechanisms | ESPEYB16

4.11. Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice

K Mao , GF Quipildor , T Tabrizian , A Novaj , F Guan , RO Walters , F Delahaye , GB Hubbard , Y Ikeno , K Ejima , P Li , DB Allison , H Salimi-Moosavi , PJ Beltran , P Cohen , N Barzilai , DM Huffman

To read the full abstract: Nat Commun. 2018 19;9:2394.Somatopause causes the physiological decline over time in GH secretion leading to low IGF-I levels in aging subjects. GH has been proposed as an anti-aging therapy, but with no evidence of beneficial effects and with some potential risks [1,2]. Therefore, current guidelines do not recommend GH therapy as anti-aging treatme...

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ESPE Yearbook of Paediatric Endocrinology

15.7. Childhood obesity intervention studies: A narrative review and guide for investigators, authors, editors, reviewers, journalists, and readers to guard against exaggerated effectiveness claims

4.11. Late-life targeting of the IGF-1 receptor improves healthspan and lifespan in female mice

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